Most of this information came via someone in one of my yahoo groups who has cancer and has done much research on the subject. I am very thankful I found it as there are many studies relating specifically to the brain and to cancer as well. I will be ordering this ASAP.Update 2/8/2011:
I have recently read the book The Palm Oil Miracle by Dr. Bruce Fife. It is amazing how many active substances are present in this one oil. Due to to it's nutrient density and lower oxidation rate than olive oil, I have almost exclusively switched from olive oil to red palm oil. Olive oil is still better for transport as it stays liquid when cold, but I have acquired an insulated thermos so I can heat her meals ahead of time and still use this oil.
From the The Palm Oil Miracle by Dr. Bruce Fife
As a Dietary Supplement
Palm oil can be used as a dietary supplement to provide a natural source of mixed vitamin E, mixed carotenoids, vitamin K, CoQ10, squalene, sterols, and other nutrients. The easiest way to take palm oil for it's nutritional value is with foods. Use the oil in food preparation. You can also take the oil by the spoonful. One Tablespoon (15ml) of red palm oil provides the equivalent of the adult US RDA of vitamin E and Vitamin A (as provitamin A carotenes). For preschool aged children, 1 teaspoon (5ml) satisfies the US RDA for these vitamins. Children ages 6-12 take 2 teaspoons to meet these requirements.
Palm oil is also available in gel capsules for those who want the benefits but can't handle taking the oil by the spoonful. The capsules are especially beneficial when you are away from home and can't use the oil in cooking.
Palm oil is non-toxic even in large amounts. It is a food, so it doesn't have any harmful side effects often associated with drugs. You could safely eat several tablespoons. The only potential drawback you might experience if you consume large amounts of red palm oil every single day is a slight yellowing of the skin. This is caused by the accumulation of carotenes in the skin. Carotenes, as you recall, are the pigments that give vegetables their orange color. This condition is not harmful in any way, and actually provides a great deal of protection to the skin from UV radiation and pollution. This condition is only temporary and will eventually go away if you stop eating the oil. Eating a couple of tablespoons of red palm oil a day is not enough to color the skin. You would have to eat a large amount of the oil daily for an extended period of time for your skin to accumulate enough to becom noticeable.
For those people who are not accustomed to eating much oil, you should be aware that, if you start adding 1 or more tablespoons of oil into your diet, it could loosen your bowels somewhat. This too is only a temporary condition. As your body adjusts to a larger amount of fat in the diet, you will no longer have this experience. If at first you experience loose bowels, all you need to do is cut back on the amount of oil you are using. As your body adjusts to the added fat, you can gradually increase the amount of oil you consume. Generally, if you replace the oil you normally use in your diet with palm oil, the amount of fat you are consuming remains the same and you will not notice any difference.
It is best to consume the oil with foods, either by cooking food in the oil or taking the oil along with meals. The oil improves the absorption of nutrients in the food. Also, oil digests more readily with food so there is less chance of experiencing abdominal discomfort or loose bowels.
Approximate content of major nutrients in red palm oil per 1 tablespoon (14g) serving.
Vitamin E
- Alpha-tocopherol 2.26 mg
- Alpha-tocotrienol 2.97 mg
- Gamma-tocotrienol 4.68 mg
- Delta-tocotrienol 1.28 mg
- Total tocotrienol 8.94 mg
- Total mixed vitamin E 11.20 mg
- Alpha-carotene 2.59 mg
- Beta-carotene 3.32 mg
- Other carotenes 1.09 mg
- Total mixed carotenes 7 mg
Other
- CoQ10 600 mcg
- Sterols 6 mg
- Squalene 5mg
"Several other studies have shown that when palm oil is added into the diet, it reduces the risk of cancer and prolongs lifespan. It doesn't matter if the primary fat in the diet is soybean oil, corn oil, lard,or beef tallow, when palm oil is added or replaces these other oil, cancer incidence declines"
You may see palm oil in processed food products or in palm oil shortenings where the palm oil has been refined to remove any flavor or orange coloring (carotenoids). According to tests, this palm oil still retains approx. 60% of it's vitamin E so it still has health benefits along with the fact of it's low oxidation potential.
Research:
General Wiki on Tocotrienols (Red Palm Oil contains all forms)
http://en.wikipedia.org/wiki/Tocotrienol
More General Information
http://www.tocotrienol.org/
Detailed paper by Dr. Bruce Fife, expert on tropical oils
...Red palm oil is a virtual powerhouse of nutrition. It contains by far, more nutrients than any other dietary oil. In addition to beta-carotene, alpha-carotene, and lycopene it contains at least 20 other carotenes along with vitamin E, vitamin K, CoQ10, squalene, phytosterols, flavonoids, phenolic acids, and glycolipids. Palm oil is one of the richest natural sources of vitamin E. In addition to ordinary vitamin E, it also contains the highest amount of a super potent form of vitamin E known as tocotrienol. There are four tocotrienols. Palm oil contains all of them. These tocotrienols have up to 60 times the antioxidant activity of ordinary vitamin E. The combination of vitamin E, tocotrienols, carotenes, and other antioxidants makes palm oil a super antioxidant food.
...Studies show palm tocotrienols inhibit the growth of skin, stomach, pancreas, liver, lung, colon, prostate, breast and other cancers. Most of the research to date has been done with breast cancer where tocotrienols show great promise. They not only prevent cancer from taking hold but actively block its growth and initiate apoptosis—a process where diseased cells commit suicide. This is a normal process that is programmed into all of our cells in order to remove old and diseased cells
...The antioxidant power of palm oil has also shown to be of benefit in protecting against neurological degeneration. Two of the most significant factors that affect brain function are oxidative stress and poor circulation. Oxidative stress generates free radicals that damage brain and nerve tissue. Poor circulation affects the brain by restricting oxygen and glucose which are vital for proper brain function. Researchers have found correlations between oxidative stress and reduced blood flow to the brain to senile dementia, Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and even schizophrenia. All of these conditions involve brain cell death.
...Initial research has been so impressive that cancer researchers have called tocotrienols the most powerful natural anticancer substances known to science (Yano, 2005).
http://www.americanpalmoil.com/publications/Red%20Palm%20Oil.pdf
This study demonstrated that oral supplementation of the palm tocotrienol complex acts on key molecular checkpoints (c-Src and 12-Lipoxygenase) to protect against glutamate- and stroke-induced neurodegeneration and ultimately protect against stroke in vivo. This would be cancer relative to potential strokes during a brain surgery or potential brain bleeds from tumors.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1829173/?tool=pmcentrez
Tocotrienols from palm oil as potent inhibitors of lipid peroxidation and protein oxidation in rat brain mitochondria
...This fraction from palm oil can be considered a natural antioxidant supplement capable of protecting the brain against oxidative damage and thereby from the ensuing adverse alterations.
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0G-3YB9VJ8-22&_user=10&_coverDate=08%2F11%2F1
***Suppression of tumor growth by palm tocotrienols via the attenuation of angiogenesis.
...In conclusion, this study showed that palm tocotrienols exhibit anti-angiogenic properties that may assist in tumor regression.
http://www.ncbi.nlm.nih.gov/pubmed/19373610
***The effect of dietary carotenoids on lung tumorigenesis induced by intratracheally instillated diesel exhaust particles.
...palm oil carotene was suggested to prevent lung tumorigenesis by its protective effect on DNA from active oxygen.
http://www.ncbi.nlm.nih.gov/pubmed/11349888?dopt=Abstract
Reduction of DNA damage in older healthy adults by Tri E Tocotrienol supplementation.
http://www.ncbi.nlm.nih.gov/pubmed/17884341
Long-term administration of tocotrienols and tumor-marker enzyme activities during hepatocarcinogenesis in rats.
...Tocotrienol supplementation attenuated the impact of the carcinogens in the rats.
http://www.ncbi.nlm.nih.gov/pubmed/8102564
"d-Dlta-tocotrienol-mediated suppression of the proliferation of human PANC-1, MIA PaCa-2, and BxPC-3 pancreatic carcinoma cells".
http://www.ncbi.nlm.nih.gov/pubmed/19346993
Effect of tocotrienols on the growth of a human breast cancer cell line in culture.
...Their effect on the ability of these cells to form colonies also was studied, and it was found that TRF inhibited PE, whereas alpha Tocopherols had no effect. These results suggest that the inhibition is due to the presence of tocotrienols in TRF rather than alpha Tocopherols.
http://www.ncbi.nlm.nih.gov/pubmed/8614304
Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status.
http://www.ncbi.nlm.nih.gov/pubmed/9625593
Inhibition of Proliferation of Estrogen Receptor-Negative MDA-MB-435 and -Positive MCF-7 Human Breast Cancer Cells by Palm Oil Tocotrienols and Tamoxifen, Alone and in Combination1,2
...These results suggest that tocotrienols are effective inhibitors of both estrogen receptor-negative and -positive cells and that combinations with tamoxifen should be considered as a possible improvement in breast cancer therapy.
http://jn.nutrition.org/cgi/content/full/127/3/544S
Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols.
http://www.ncbi.nlm.nih.gov/pubmed/10227040
Combined Treatment of -Tocotrienol with Statins Induce Mammary Tumor Cell Cycle Arrest in G1
http://en.wikipedia.org/wiki/Tocotrienol#cite_note-40
Gamma-tocotrienol suppresses prostate cancer cell proliferation and invasion through multiple-signalling pathways.
http://www.ncbi.nlm.nih.gov/pubmed/19002171
Evidence of γ-Tocotrienol as an Apoptosis-Inducing, Invasion-Suppressing, and Chemotherapy Drug-Sensitizing Agent in Human Melanoma Cells
http://www.informaworld.com/smpp/content~db=all?content=10.1080%2F01635580802567166
Chemoprevention of tocotrienols: the mechanism of antiproliferative effects.
http://www.ncbi.nlm.nih.gov/pubmed/19367124
Vitamin E and cancer: An insight into the anticancer activities of vitamin E isomers and analogs.
http://www.ncbi.nlm.nih.gov/pubmed/18512238
Anti-angiogenic activity of tocotrienol.
Our findings suggest that tocotrienol has potential use as a therapeutic dietary supplement for minimizing tumor angiogenesis.
http://www.ncbi.nlm.nih.gov/pubmed/12913317
***Effects of oil palm phenolics on tumor cells in vitro andin vivo
http://www.academicjournals.org/ajfs/PDF/Pdf2010/Aug/Sekaran%20et%20al.pdf
Sources:
http://www.tropicaltraditions.com/
http://www.wildernessfamilynaturals.com/mm5/merchant.mvc?Screen=PROD&Store_Code=WFN&Product_Code=NPO1&Cat
http://www.junglepi.com/products/red_palm.html
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